http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1411701-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4655b70cbfba352025a1d2393b449e77 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D461-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-475 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-475 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D461-00 |
| filingDate | 1973-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1975-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1411701-A |
| titleOfInvention | Compositions containing compounds of the eburnane structure |
| abstract | 1411701 Medicines comprising alkaloids SYNTHELABO 25 May 1973 [26 May 1972 21 June 1972 9 May 1973] 25081/73 Heading A5B Orally administrable pharmaceutical compositions comprise a compound having the eburnane structure and ascorbic acid and/or a salt thereof or a complex with an aromatic heterocyclic compound containing at least one nitrogen atom, the weight ratio of the said substance to the ascorbic acid substance (expressed as ascorbic acid) being in the range 4:1 to 1:200. The term "compound having the eburnane structure" means vincamine and related alkaloids having a structure covered by the general formula: wherein R 1 represents -CH 2 OH or a carboxyl group or a salt, ester or amide thereof, R 2 represents a hydrogen atom or a hydroxyl group and R 3 represents a hydrogen atom or R 2 and R 3 together represent an additional bond between the two C atoms to which they are attached or R 1 is OH and R 2 and R 3 are both H atoms or R 1 and R 2 together represent =O and R 3 is H, or an acid addition salt or N-oxide of such a compound. The resorption of the alkaloid in the digestive tract is stated to be greater in the compositions of the invention than when the alkaloid is administered alone. The compositions may be put up in conventional orally administrable forms such as tablets, coated tablets, pills, capsules and drinkable preparations containing conventional excipients. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-8809662-A1 |
| priorityDate | 1972-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 23.