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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-08
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-08
filingDate 1972-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1975-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber GB-1405135-A
titleOfInvention Antileukaemic ansa macrolides
abstract 1405135 Anti-tumour medicaments S M KUPCHAN 23 Aug 1972 39181/72 Heading A5B [Also in Division C2] Pharmaceutical compositions, suitable for parenteral administration, contain macrolides of the formula: where R is CH 3 (Maytansine), CH 2 CH 3 (Maytanprine) or CH(CH 3 ) 2 (Maytabutine) or 9-O- (3-bromopropyl) maytansine and pharmaceutically acceptable carriers and, if desired, other active ingredients such as mechlorethamine hydrochloride, S-[bis (2-chloroethyl) amino] uracil, triethylenemelamine, actinomycin C or cyloheximide. The compounds possess activity tumor inhibitory activity.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4190580-A
priorityDate 1972-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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