http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1398243-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0d269c8e41f178194d858c230c9f85e3 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-14 |
| filingDate | 1973-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1975-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1398243-A |
| titleOfInvention | Preparation of indoline derivatives |
| abstract | 1398243 1 - Phenylindolinealkyl amines PFIZER Ltd 16 Jan 1974 [20 Jan 1973] 3067/73 Heading C2C Indolines of formula in which R<SP>1</SP> and R<SP>2</SP> are each hydrogen or a lower alkyl group and R<SP>3</SP> is a C 1-4 alkyl group, are prepared by converting a 3-alkyl-1-phenyl-2- indolinone of the Formula II into an amide of Formula IV either by reaction of the 3-alkyl-1-phenyl-2- indolinone of the Formula (II) with a C 1-4 alkyl ester of acrylic acid in the presence of a base to form the corresponding 3-(2-alkoxycarbonylethyl) compound, which is then converted to the amide of the Formula (IV) or directly by reaction of the 3-alkyl-1-phenyl-2-indolinone of the Formula (II) with an acrylic amide of the formula CH 2 =CH.CONR<SP>1</SP>R<SP>2</SP> in the presence of a base, and the amide is then reduced and a compound of Formula (I) is isolated as the product. |
| priorityDate | 1973-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 19.