http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1398099-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7b4beef0c137d9094e6918ee382be22f |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-35 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J23-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-35 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-352 |
| filingDate | 1972-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1975-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1398099-A |
| titleOfInvention | Substituted xanthone carboxylic acid compounds |
| abstract | 1398099 Xanthone carboxylic acids SYNTEX (USA) Inc 12 July 1972 [23 Aug 1971] 38515/74 Divided out of 1398096 Heading C2C The invention comprises compounds of the formula wherein one X is H and the other X is a group of formula wherein R is OH, NH 2 , or mono- or di-(C 1 -C 5 ) alkylamino; and pharmaceutically acceptable, non-toxic esters, amides and salts thereof. They may be obtained by treating a 5- or 7-mereaptoxanthone-2-carboxylic acid with Cl 2 under acidic conditions to give the corresponding 5- or 7- chlorosulphonyl substituted compounds and treating the latter either with an inorganic base other than NH 3 to give the corresponding 5- or 7-sulphoxanthone-2-carboxylic acids; or with NH 3 or a mono- or di-(C 1 -C 5 ) alkylamine to give the corresponding 5- or 7-sulphamoyl, -N-monoalkylsulphamoyl, and -N,N-dialkylsulphamoylxanthone-2-carboxylic acids; and optionally converting any of these products to their corresponding pharmaceutically acceptable, non-toxic esters, amides or salts. Examples are given for the preparation of these compounds. Compounds of the above formula are useful for inhibiting the effects of allergic reactions, also as smooth muscle relaxants and as vasodilators. The compositions containing these compounds optionally together with other pharmaceutical agents, e.g. antibiotics and hormonal agents, may be administered orally, topically, parenterally, or by inhalation and in the form of either solid, liquid or gaseous doses including tablets, suspensions and aerosols. |
| priorityDate | 1971-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 21.