http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1394859-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0efa077d881a96aeb1e29b21ef1bbb58 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-03 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-03 |
| filingDate | 1972-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1975-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1394859-A |
| titleOfInvention | N-substituted 1-aminomethylindans |
| abstract | 1394859 N-substituted-1-aminomethylindanes BADISCHE ANILIN- & SODA-FABRIK AG 25 July 1972 [26 July 1971] 34689/72 Heading C2C Novel compounds I and salts thereof in which R 1 is C 1-6 alkyl or C 6-8 cycloalkyl and R 2 is C 1-6 alkyl substituted by phenyl hydroxyl, alkoxy or dialkyl amino or NR 1 R 2 represents an N-containing, 5 to 7 membered heterocycle which may be substituted by alkyl radicals and which may contain a further N or O atom in the ring are prepared by reductive amination of 1- formyl indane. Compounds prepared are those in which R 1 is methyl and R 2 is 3-phenyl-butyl or NR 1 R 2 is an optionally C 1-3 alkylated pyrrolidine, piperidine, hexahydroazepine, piperazine or morpholine ring. Stereoisomers may be resolved using C -1 dibenzoly-tartaric acid. Compounds I lower blood pressure, inhibit inflammation ad have parasympatholytic and CNS stimulating properties and form a pharmaceutical composition which may be administered orally or parenterally. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0361577-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0164697-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0164697-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5200423-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5021458-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5334628-A |
| priorityDate | 1971-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.