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filingDate 1973-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1975-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber GB-1392270-A
titleOfInvention Indan-1-carboxamide derivatives
abstract 1392270 lndan-1-carboxamide derivatives TAKEDA YAKUHIM KOGYO KK 7 Dec 1973 [7 Dec 1972] 56780/73 Heading C2C Novel compounds of the Formula I wherein X is hydrogen or halogen; R 1 is hydrogen, phenyl or alkyl optionally substituted with hydroxy; and R 2 is alkyl optionally substituted with hydroxy, phenyl or N,N-dialkylamino; hydroxy, unsubstituted amino or optionally, mono- or dialkyl-amino, phenyl or halophenyl; phenyl optionally substituted with halogen, mono or dialkyl, an alkoxy or a sulphamoyl; or R 1 and R 2 together with the adjacent nitrogen atom form a piperidino, morpholino or piperazino optionally substituted with an alkyl group on the 4-nitrogen, wherein alkyl groups have 1 to 6 carbon atoms and alkoxy groups have 1 to 3 carbon atoms, and salts thereof may be prepared by reacting the carboxylic acid II or a reactive derivative thereof with compound III Pharmaceutical compositions of the compounds I alone or with the usual excipients show analgesic, anti-inflammatory, antipyretic and anti-rheumatic activity when administered orally or parenterally.
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Total number of triples: 31.