http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1391443-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_232361c9031a709144573276863c462b |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-57 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J5-0053 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-573 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-57 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J5-00 |
| filingDate | 1971-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1975-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1391443-A |
| titleOfInvention | Ester of betamethasone and its 9alpha-chloro analogue |
| abstract | 21-Adamantoyloxysteroids of the formula I <IMAGE> in which A is hydroxyl and B is fluorine or chlorine, or A and B together represent a carbon-carbon bond, are distinguished by a systemic antiinflammatory activity with a duration of action which is considerably prolonged by comparison with known antiinflammatory steroids and, furthermore, adversely affect the function of the adrenals considerably less by comparison with known steroids. The said compounds are prepared by reacting the corresponding compounds which are substituted in position 21 by hydroxyl, iodine or a hydrocarbon-sulphonyloxy group with a compound supplying the adamantoyl group, namely a halide, anhydride or salt of adamantane-1-carboxylic acid. |
| priorityDate | 1971-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 27.