http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1389368-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_56ee5285e8e8edccb061046ff20da7a6 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S436-903 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-146666 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-728 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-72 |
| filingDate | 1973-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1975-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1389368-A |
| titleOfInvention | Diagnostic agent |
| abstract | 1389368 Bilirubin test paper BOEHRINGER MANNHEIM GmbH 14 Aug 1973 [17 Aug 1972] 38430/73 Heading G1B A test strip for detection of bilirubin in body fluids comprises (a) an absorbent carrier, (b) a diazonium salt of formula: wherein R 1 and R 2 are halogen, alkyl or alkoxy and R 3 and R 4 are hydrogen, halogen, nitro, alkyl or alkoxy such that the benzene ring has 1 to 3 halogen substituents or a nitro-substituent but not both and X is an anion and (c) an acid. The carrier may be filter paper, glass fibre paper, or fabric or fleece made from acid-resistant synthetic fibres. The diazonium salt may be a diazonium fluoborate of 2, 6-dichlorobenzene, 2-methoxy-4, 6-dibromobenzene, 2-methyl-4, 6-dibromobenzene, 2-methyl-4-chloro-6- bromobenzene, 2-methyl-4-bromo-6-chlorobenzene, 4-methyl-2, 6-dibromobenzene, 4- ethyl-2, 6-dibromobenzene, 4-methyl-2, 6- di-iodobenzene, 2, 6-dimethyl-3-nitrobenzene, 2-ethoxy-4, 6-dibromobenzene, 4-methoxy-2, 6-dibromobenzene, 2, 6-dimethoxy-3, 5-dibromobenzene, 2, 6-dimethoxy-4-nitrobenzene, 2, 5-dimethyl-4, 6-dibromobenzene, 2, 4, 6- tribromobenzene, 2-methyl-4, 6-dibromo-5- chlorobenzene, 2, 4,6-tribromo-3-methoxybenzene and 2, 3, 6-tribromobenzene, 2, 4, 6- trichlorobenzene-diazonium toluene sulphonate and 2, 4, 6-tribromobenzene-diazonium naphthalene disulphonate. The diazonium salt may be prepared in situ from sodium nitrite and the corresponding aniline, e.g. 2-methyl-6-chloroaniline, 2, 6-dimethyl-3-bromoaniline, 2, 6-dimethyl -4-bromoaniline, 2, 6-dimethoxy-3-bromoaniline and 2, 6-dimethoxy-4-chloroaniline. The acid may be metaphosphoric or citric acid. The strip may also contain an activator for the diazobilirubin coupling reaction, a phosphate of formula: wherein Rs and R6 are organic groups, a stabilizer and a wetting agent. The carrier may be stuck to the end of a narrow strip of synthetic resin foil, or sealed between two sheets of synthetic resin film or between a film and a meshwork. |
| priorityDate | 1972-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 71.