http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1383766-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5712b4838bdb16ebbc41121239e165b9 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D499-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-68 |
| filingDate | 1971-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1974-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1383766-A |
| titleOfInvention | Penicillins |
| abstract | 1383766 α - Guanidino - benzylpenicillins BEECHAM GROUP Ltd 6 Sept 1972 [4 Aug 1971] 7535/74 Divided out of 1383765 Heading C2C Novel penicillins having the general formula (II) and salts thereof, wherein R is hydrogen or C 1-4 alkyl, are prepared by reacting 6-aminopenicillanic acid or an ester or silyl derivative thereof with an acid addition salt of a compound of Formula (IV) wherein R is hydrogen or C 1-4 alkyl, R 2 is an optionally protected hydroxyl group and X is an optionally salted hydroxyl group or a group formed in situ by reaction of an optionally salted hydroxyl group with a carbodiimide or a carbonyldiimidazole, and thereafter removing any silyl, esterifying or other protecting groups present. The penicillins (II) or their pharmaceutically acceptable salts are used to prepare antibiotically active pharmaceutical compositions. The compounds (IV) are produced by reacting an appropriate α-amino-phenylacetic acid with O-methyl isourea; they are then converted to their HCl salts. |
| priorityDate | 1971-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 23.