http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1383291-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_97a285d8ecd0184a7e5d89a1e4e07997 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D265-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-22 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D265-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-52 |
| filingDate | 1973-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1974-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1383291-A |
| titleOfInvention | N-phenyl amidines |
| abstract | 1383291 N-phenylamidines BRISTOLMYERS CO 22 May 1973 16343/74 Divided out of 1377353 Heading C2C The invention comprises compounds of formula and their pharmaceutically acceptable acid addition salts, wherein B is X, Y are each H, halogen, CF 3 or C 1-4 alkyl or alkoxy; Z is Ph, 2-thienyl or 2-furyl; and A is 5,6 - dihydro - 2H - 1,4 - oxazin - 3 - yl, 5,6- dihydro-2H-1,4-thiazin-3-yl, or are of the following #<SP>1</SP>-2-heterocyclyl radicals optionally containing 1 or 2 C 1-4 alkyl substituents, namely, pyrrolinyl, tetrahydropyridyl or tetrahydroazepinyl. These compounds are prepared by reacting in presence of POCl 3 and an inert organic solvent, a compound of Formula III (but where B is -NH-alkylene(C 1-4 )-Z), with the appropriate acyclic or cyclic amide. Therapeutic compositions having diuretic, anti-thrombogenic, smooth muscle relaxant, brochodilating or anti-inflammatory activity comprise compounds of the above formula, and may be administered orally (preferably) or parenterally. |
| priorityDate | 1970-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 20.