http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1377956-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5929f2d6f4dba84be8dd3a8ba633db12 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D499-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D499-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-20 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C53-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-06 |
| filingDate | 1971-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1974-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1377956-A |
| titleOfInvention | Antibacterial compounds |
| abstract | 1377956 Cyclohexen-1-ylglycinamido penicillins and cephalosporins TAKEDA YAKUHIN KOGYO KK 11 Oct 1971 [12 Oct 1970 24 May 1971 3 Aug 1971 28 Aug 1971] 47177/71 Heading C2C Novel α - amino - cyclohexen - 1 - yl - acetamido - penicillanic, cephalosporanic and desacetoxycephalosporanic acids of Formula (I) and their acetone adducts of Formula (II) and salts of these compounds, wherein A is a residue of 2,2-dimethyl-3-carboxypenam, 3- acetoxymethyl - 4 - carboxyceph - 3 - em or 3- methyl - 4 - carboxyceph - 3 - em, the residue being attached to the cyclohexenylglycinamido group at the 6-position of the penam ring or at the 7-position of the cephem ring, are prepared by reacting cyclohexen-1-ylglycine or its N-acylating derivative with 6-APA, 7-ACA or 7-ADCA or a salt or easily hydrolysable ester thereof and if required, hydrolysing to remove the esterifying group, and if the compounds (II) are required, reacting the product with acetone. The production of 7-(D(-)1<SP>1</SP>-cyclohexenylglycinamido)-cephalosporanic acid methylsulphenylmethyl ester is illustrated, followed by reaction of the ester with acetone and hydrolysis to remove the ester group to give the corresponding free acid of Formula (II). The inventive compounds may be made up into pharmaceutical compositions having antibacterial activity by admixture with a pharmaceutically acceptable diluent or carrier. |
| priorityDate | 1970-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.