http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1377610-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_249d88916b29a57a878f8702290b5d33 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-10 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-10 |
filingDate | 1970-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1974-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | GB-1377610-A |
titleOfInvention | 5-piperidine-4-spiro- oxazolidinones method for their preparation and applications thereof |
abstract | 1377610 5 - (Piperidine - 4 - spiro) - oxazolidinones LABORATOIRES JACQUES LOGEAIS 30 Nov 1971 [19 Dec 1970] 60430/70 Heading C2C Novel 5 - (piperidine - 4 - spiro) - oxazolidinones of the general formula wherein R is a hydrogen atom or an alkyl, alkenyl, alkynyl or phenyl group, R<SP>1</SP> is a hydrogen atom or alkyl group, R<SP>2</SP> is a hydrogen or halogen atom or an alkyl group and B is an oxygen atom or a methylene, ethylene or -O-CHR<SP>3</SP>- group, in which the oxygen atom is bonded to the aromatic nucleus and R<SP>3</SP> is a hydrogen atom or alkyl group, and non-toxic acid addition salts thereof are prepared by condensing a 5-(piperidine-4-spiro)-oxazolidinone and a phenoxyethyl halide of the respective general formulĀµ wherein X is a halogen atom, followed optionally by salifying the product. Pharmaceutical compositions having adrenolytic activity comprise, as active ingredient, a 5-(piperidine-4-spiro)-oxazolidinone of the first general formula above or a non-toxic acid addition salt thereof, together with a therapeutically acceptable vehicle, arid may be administered orally or parenterally. |
priorityDate | 1970-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 17.