http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1377265-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c7ad58d3c0b071069a8ee0cb8c8ba2e8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P33-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C335-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-18 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C335-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P33-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D279-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-426 |
| filingDate | 1972-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1974-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1377265-A |
| titleOfInvention | Phenylimino-3-aza 1-thia-cycloalkanes their preparation and their medicinal use |
| abstract | 1377265 Phenylimino - 3 - aza - 1 - thia - cycloalkanes BAYER AG 13 Sept 1972 [14 Sept 1971 8 March 1972] 42552/72 Heading C2C Novel compounds (I) (including salts thereof) in which R is a straight-chain or branched alkyl, alkenyl or alkynyl group which is optionally substituted by a halogen or alkoxy radical; and R<SP>1</SP> is a hydrogen atom or a straight-chain or branched alkyl or alkenyl group (which is optionally substituted by an alkoxy group), or a -COR<SP>6</SP> or -SO 2 R<SP>7</SP> group; in which R<SP>6</SP> is a hydrogen atom or a straight-chain or branched alkyl, alkenyl, alkynyl, alkoxy, alkenyloxy, alkynvloxy, alkoxyalkyloxy or alkoxyalkyl group (which is optionally substituted by a halogen, trifluoromethyl, nitrile, hydroxyl, acyloxy, alkoxy or oxo radical), or a cycloalkyl, cycloalkenyl or cycloalkadienyl group (which is optionally substituted by one or more alkyl groups), or a cycloalkylalkyl, benzocycloalkylalkyl, tetrahydrofuryl, tetrahydrofurfuryl or tetrahydropyranyl group (which is optionally substituted by an alkyl group), or a trifluoromethyl group, or a carbalkoxyalkyl group, or a cycloalkylalkoxy group, or a cycloalkoxy group, or a tetrahydrofurylalkoxy group, or a phenylalkoxy, phenoxyalkoxy, phenoxy, phenylalkyl, phenyl, phenylalkenyl or naphthyl group (in which the aromatic ring is optionally substituted by one or more alkyl, alkenyl, alkoxy, hydroxyl, acyloxy, nitro, chloro, bromo, fluoro, trifluoromethyl, nitrile, carbethoxy, alkylsulphonyl, acylamino or alkylsulphonylamino radicals), or a heteroaromatic ring system (which can optionally be substituted by one or more alkyl groups), or a furylalkyl, thienylalkyl, indolylalkyl, furylalkyloxy or thienylalkoxy group (which is optionally substituted by one or more alkyl groups), or a phenylalkyl group (in which the alkyl part is substituted by a hydroxyl, acyloxy or alkoxy group); and R<SP>7</SP> is a straight-chain or branched alkyl or alkenyl group, or an aralkyl, cycloalkyl or cycloalkylalkyl group; R<SP>2</SP> and R<SP>3</SP> can be identical or different and is each a hydrogen atom or a straight-chain or branched alkyl, alkenyl or alkoxy group, or a halogen, nitrile or trifluoromethyl radical; R<SP>4</SP> and R<SP>5</SP> are each a hydrogen atom or an alkyl group; and n is 2 or 3, are made by a wide variety of standard methods including the cyclization of appropriate thioureas. The following intermediates are also prepared: N - (4 - carboethoxyaminophenyl) - N<SP>1</SP> - methyl- N<SP>1</SP> - (# - hydroxy- and -chloro - ethyl) - thioureas, N - (4 - nitrophenyl) - N<SP>1</SP> - methyl - N<SP>1</SP> - (#- hydroxy- and -chloro - ethyl) - thioureas, 2 - (4- nitrophenylimino) - N - methyl - thiazolidine and 2 - (4 - isobutyl - ideneaminophenylimino)- N- methyl-thiazolidine. Pharmaceutical preparations showing anthelmintic action contain (I) as active ingredient. Administration is orally, parenterally, rectally or locally. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6353006-B1 |
| priorityDate | 1971-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 33.