http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1374346-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7f6e33603375c486b0ab3505830af9e8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-06 |
| filingDate | 1972-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1974-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1374346-A |
| titleOfInvention | Pharmaceutically active isoxazolone derivatives |
| abstract | 1374346 Isoxazolone derivatives SANKYO CO Ltd 24 Nov 1972 54443/72 Heading C2C Novel isoxazolone derivatives of the formula wherein R<SP>1</SP> is H, halogen or alkyl, R<SP>2</SP> is H, alkyl, alkoxycarbonyl or aryl, or R<SP>1</SP> and R<SP>2</SP>, together with the carbon atoms to which they are attached, represent a fused benzene ring with the isoxazoline ring and -NA) is an unsubstituted or substituted 5-7-membered saturated heterocyclic ring optionally containing further hetero atoms are prepared by 4-R<SP>1</SP>-5-R<SP>2</SP>- 2-haloformyl - 4 - isoxazolin - 3 - ones or 2- haloformylbenzisoxazolin-3-ones with the appropriate heterocyclic compounds or by reacting 4-R<SP>1</SP>-5-R<SP>2</SP>-3-hydroxyisoxazoles or 3-hydroxybenzisoxazoles with compounds of the formula wherein X is halogen. 2 - Chloroformyl - 4 - isoxazolin - 3 - one is obtained by reacting phosgene with 3-hydroxyisoxazole. Pharmaceutical compositions, suitable for oral or parenteral administration, contain the above novel compounds and pharmaceutical carriers or diluents. The compounds possess analgesic, anti-inflammatory, antitussive and anti-hypertensive activities. |
| priorityDate | 1972-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 20.