http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1369247-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_05a203d85ee01909eaf728dc16f0f6cb |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C229-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-215 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C275-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C255-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C291-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D317-58 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-215 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C215-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D317-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C291-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C275-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C215-14 |
| filingDate | 1971-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_83f48ff763bd76b4e899836be2c99c13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9184a203c26e2de87fa746c1a65b414b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_87fef1ceadd500d836cc4fb6f8b043eb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ad54230c17eeb464bf3962242530e56 |
| publicationDate | 1974-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1369247-A |
| titleOfInvention | Amines the preparation thereof and their use in pharmaceutical compositions |
| abstract | 1369247 Diamine and triamine derivatives PFIZER Inc 3 Aug 1971 [7 Aug 1970 24 May 1971] 36522/71 Heading C2C [Also in Division A5] The invention comprises novel therapeutic compounds (I) and the di-N-oxides, methonium iodides and non- toxic acid addition salts thereof wherein R 1 is alkyl of from 1 to 20 carbon atoms, aralkyl, aryloxyalkyl, hydroxyalkyl of from 2 to 8 carbon atoms or R 2 is alkyl of from 6 to 20 carbon atoms, aralkyl or aryloxyalkyl of from 12 to 24 carbon atoms or as Formula II above, R‹ is alkoxy of from 1 to 18 carbon atoms; each of R<SP>1</SP> and R<SP>11</SP> is hydrogen, alkyl, or alkoxy of from 1 to 18 carbon atoms; or R<SP>1</SP> and R<SP>11</SP>; when taken together, are methylenedioxy; provided that the total number of carbon atoms in R‹, R<SP>1</SP> and R<SP>11</SP> is from 5 to 48; R 3 is hydrogen, alkyl of from 1 to 20 carbon atoms, hydroxyalkyl of from 2 to 8 carbon atoms, phenylcarbamoyloxy-(alkyl), #- carboxyalkanoyloxy-(alkyl), allyl, alkanoyl of from 1 to 6 carbon atoms, alkanoyloxy-(alkyl), carbo alkoxy alkyl, carboxy (alkyl), alkoxy (alkyl) or gem-di-(alkoxy) alkyl; R 4 is hydrogen, alkyl of from 1 to 8 carbon atoms, hydroxyalkyl of from 2 to 8 carbon atoms, carbo alkoxy alkyl, alkanoyloxy-(alkyl), carboxy-(alkyl), alkoxy- (alkyl), phenylcarbamoyloxy-(alkyl), #-carboxyalkanoyloxy-(alkyl), allyl, dihydroxyalkyl of from 3 to 8 carbon atoms or morpholinoethyl; R 3 and R 4 when taken together with the nitrogen to which they are attached are morpholino; X is straight chain alkylene of from 2 to 6 carbon atoms or X<SP>1</SP> is X, phenylenedimethylene or m is 0 or 1, with the provisos that only one of X and X<SP>1</SP> is and when X<SP>1</SP> is phenylenedimethylene, m is 0; and when X is alkylene, m is 1 and each of R 1 and R 2 is as Formula II. They are made by standard methods. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4987130-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5763495-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5902772-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0008696-A1 |
| priorityDate | 1970-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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