http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1364779-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4da51240309dc01cd248e0e244a3cd70 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C45-673 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C49-173 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-33 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-33 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-426 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-425 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C45-67 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C49-173 |
| filingDate | 1972-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1974-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1364779-A |
| titleOfInvention | Thiazole derivative |
| abstract | 1364779 3 - (N,N - Diisopropyl - acetamido)- 4 - methyl - 5 - (beta - hydroxyethyl) - rhiazolium bromide SOC D'ETUDES DE PRODUITS CHIMIQUES 18 April 1973 [9 May 1972] 21567/72 Heading C2C The invention comprises 3-(N,N-diisopropylacetamido) - 4 - methyl - 5 - (beta - hydroxyethyl)-thiazolium bromide having the formula It may be prepared by reacting, in stoichiometric proportions, N,N-diisopropyl-bromacetamide with 4-methyl-5-hydroxyethyl thiazole in boiling butanol. 1364783 Pyrazole derivatives F HOFFMANN-LA ROCHE & CO AG 20 Oct 1972 [22 Oct 1971] 48432/72 Heading C2C Compounds of the general formula wherein R represents a lower alkyl group, which may be substituted with halogen, hydroxy, lower alkoxy, lower alkoxycarbonyl or carboxy or a lower alkenyl group, R 1 represents a hydrogen or halogen atom or a lower alkyl or lower alkoxy group and R 2 represents a grouping of the formula wherein R 3 represents a hydroxyl, lower alkanoyloxy, lower alkoxycarbonyloxy or lower alkoxy group (the alkoxy group being optionally substituted with halogen or lower alkoxy) or a phenylcarbonyloxy, phenyl (lower alkylcarbonyloxy), phenyl-(lower alkenylcarbonyloxy), pyridyl-(lower alkylcarbonyloxy) or pyridyl carbonyloxy group (the phenyl residues and the pyridyl residues being optionally substituted by lower alkyl, lower alkoxy or halogen), R 4 represents a lower alkyl or phenyl group and R 5 represents a hydrogen atom or a lower alkyl group or R 4 and R 5 together with the carbon atom to which they are attached represent a 5-, 6- or 7-membered alicyclic ring and salts thereof are claimed per se. The compounds of the invention may be prepared by a process which comprises (a) reacting a compound of the general formula wherein R and R 1 have the significance given in claim 1 and R 6 represents a lower alkyl group, with hydroxylamine in an inert solvent to give an amidoxime of the general formula or (b) reacting the preceding amidoxime with an appropriate lower acylating agent or a chloroformic acid lower alkyl ester or reacting an alkali metal or alkaline earth metal salt of the above amidoxime with a lower alkylating agent or (c) reacting the above amidoxime with a carbonyl compound of general formula or an acetal thereof and (d) splitting up a racemate obtained into the optical antipodes, if desired, and (e) converting a compound obtained into a salt, if desired. The term "lower" used throughout means having up to 5 carbon atoms. |
| priorityDate | 1972-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 45.