http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1363399-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_80149ab0af283f12a2cd2b1761d4d1a7 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K33-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C01F7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C01F5-24 |
| filingDate | 1973-04-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1974-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1363399-A |
| titleOfInvention | Method of preparing an antacid pharmaceutical product |
| abstract | 1363399 Al hydroxide on basic Mg carbonate ROTTA RESEARCH LABORATORIUM SpA 4 April 1973 [13 April 1972] 16192/73 Heading C1A [Also in Division A5] A method of preparing a product which consists essentially of amorphous aluminium hydroxide supported on basic magnesium carbonate crystals and may comprise tiny grains of basic magnesium carbonate wholly enrobed by an amorphous aluminium hydroxide film is characterized by the steps of: (a) dissolving in water aluminium sulphate hydrate Al2(SO4)3.- 18H2O in a proportion of 1400-4000 ml. water per mole sulphate; (b) adding to the resulting solution while stirring aqueous ammonia of a 27-30% by weight concentration at a pouring rate of 0À100-0À160 mole/min per mole dissolved sulphate, till a final pH of 9À75-9À81 is reached, thereby uniformly dispersing aluminium hydroxide Al(OH)3 in gelatinous form; (c) uniformly dispersing in the said dispersion basic magnesium carbonate pentahydrate (MgCO3)4.Mg(OH)2.5H2O in particles not exceeding 50 microns in size, in a quantity corresponding to 1À0-1À2 atoms Mg to one atom Al present in the dispersion; (d) filtering the dispersion from steps (c); (e) removing from the filtering residue by washing with water ammonium sulphate trapped therein as a by-product of step (b); (f) replacing by acetone at least 60% by weight of the water impregnating the washed residue; (g) drying the acetoneimpregnated residue at a temperature of 60- 80 C. to obtain a solid particulate product containing less than 1% by weight imbibition water; (h) mechanically reducing the product particles to a size not exceeding 10 microns. |
| priorityDate | 1972-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 37.