http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1353069-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5929f2d6f4dba84be8dd3a8ba633db12 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-898 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H17-08 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-08 |
| filingDate | 1971-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1974-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1353069-A |
| titleOfInvention | Method of producing esters of beta-5050 or tetrahydro-beta-5050 |
| abstract | 1353069 Antibiotic B5050 derivatives TAKEDA YAKUHIN KOGYO KK 2 July 1971 [2 July 1970 16 Nov 1970 1 Dec 1970] 31038/71 Heading C2A The invention comprises esters of the antibiotic designated B 5050 which have the general Formula I: wherein R 1 may be propionyl or acetyl and R 2 may be i-valeryl, propionyl or acetyl. The esters are those in which the secondary hydroxyl groups at positions 9 and 2<SP>1</SP> are esterified, e.g. by acetic acid, propionic acid, butyric acid or crotonic acid. The invention also comprises esters of tetrahydro B-5050. Tetrahydro B-5050 is a compound in which the 10-11 double bond and the epoxy group are hydrogenated, i.e. a third secondary hydroxyl group at position 13 results. Thus triesters of the tetrahydro form of B-5050 are possible. A process for introducing an ester group into antibiotic B-3050 or tetrahydro B-5050 or tetrahydro B-5050 in one step or stepwise comprises reacting B-5050, tetrahydro B-5050 or a 9- esterified form of B-5050 is reacted with an esterifying agent containing an ester group of 2-7 carbon atoms derived from an organic carboxylic acid. One or more of the 2<SP>1</SP>, 9 or 13 hydroxyl groups may be esterified. |
| priorityDate | 1970-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 23.