http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1350390-A

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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-10
filingDate 1970-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_759914bb4168fa817c4ac73c45153603
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publicationDate 1974-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber GB-1350390-A
titleOfInvention Phosphatide separation
abstract 1350390 Separation of phosphatides UNILEVER Ltd 22 Sept 1971 [23 Sept 1970] 45295/70 Heading C2P An N-acyl phosphatide is separated from a phosphatide without an acylatable amino group by acidifying a mixture comprising the phosphatides so that a 1% by weight aqueous dispersion of the mixture would have a pH of less than 3À5, and solvent fractionating the mixture with acetone and/or methyl acetate. The starting mixture of phosphatides may be obtained by acylating a mixture of N-acylatable and non- N-acylatable phosphatides, for example a mixture of cephalin (acylatable) and lecithin and inositol phosphatides (non-aeylatable). The mixture of phosphatides may also contain triglyceride oils and water. The acylating agent is preferably a carboxylic acid anhydride, and the acid by-product may be removed by distillation. The acid pH may be provided by an acid of pKa less than 3, such as hydrochloric or orthophosphoric acid. The non-acylatable phosphatides may be further fractionated by extraction with alcohol, since lecithin is more soluble than inositol phosphatides in alcohol.
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