http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1343703-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e7b6b5e393173f441c13092de9ff8205 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-811 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F8-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N11-087 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6427 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N11-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-44 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F8-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N11-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N11-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-81 |
| filingDate | 1971-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1974-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1343703-A |
| titleOfInvention | Method of chemically coupling biologically active substances to oxirane-containing polymers |
| abstract | 1343703 Chemically coupling proteins &c. to polyacrylamide or polysaccharides EXPLOATERINGS AB TBF 19 April 1971 [23 Jan 1970] 20182/71 Headings C3H C3P and C3U A method of chemically coupling an amino acid, peptide, protein, plasma protein or nucleotide to a water-insoluble polysaccharide (agar, cellulose, dextran or cross-linked dextran) or polyacrylamide involves reacting a waterinsoluble hydrophilic oxirane group-containing form of the polysaccharide or polyacrylamide with a solution of the amino acid &c. under conditions which at least partially retain the biological activity of the amino acid &c. in the coupled product. According to the Examples (1) agarose is activated with epichlorohydrin, and soyabean-trypsin-inhibitor or trypsin is coupled to the activated agarose, (2) and (3) the coupled product is used to purify trypsin and soyabean-trypsin-inhibitor, respectively, by adsorption and elution. Examples 4, 5 and 6 are broadly similar except that the polymer is obtained by activating the tosyl ester of cellulose with sodium methylate, agarose with epibromohydrin and cross-linked polyacrylamide with bis-epoxide, respectively. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111965341-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4987234-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111965341-A |
| priorityDate | 1970-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 55.