http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1341827-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b0d43ca03213c433892c1e9948cb7b17 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D- |
| filingDate | 1970-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1973-12-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1341827-A |
| titleOfInvention | Derivatives of cephalosporanic acid |
| abstract | 1341827 Silyl derivatives of 7-isocyanatocephalosporanic acid KONINKLIJKE NEDERLANDSCHE GIST-EN SPIRITUSFABRIEK NV 18 Dec 1970 [18 Dec 1969] 61842/69 Heading C3S [Also in Division C2] The invention comprises 7-isocyanatocephalosporanic acid derivatives of the formula wherein R represents a hydrogen atom, a protected hydroxy group or an acyloxy group, and E represents a carboxylic protecting group such as a silyl group of general formula (R 1 ) 3 Siin which R 1 represents C 1 -C 6 alkyl, phenyl or phenyl (C 1 -C 6 ) alkyl. In particular E may represent the trimethylsilyl group. The above compounds also include those in which R is a protected hydroxy group of formula -OSi(R 1 ) 3 in which R 1 is C 1 -C 6 alkyl, phenyl or phenyl (C 1 -C 6 ) alkyl. Examples of such compounds are trimethylsilyl esters of 7-isocyanato-cephalosporanic and 7-isocyanatodesacetoxycephalosporanic acid. The 7-isocyanate cephalosporanic acid derivatives are prepared by reacting phosgene with a cephalosporanic acid derivative of formula wherein W represents a hydrogen atom or a group (R 1 ) 3 Siin which R 1 represents a C 1 -C 6 alkyl group, phenyl group or phenyl (C 1 -C 6 ) alkyl group in an inert organic solvent, to convert the grouping W-NH- into the isocyanate group without affecting the rest of the molecule. Reference has been directed by the Comptroller to Specification 1,174,335. |
| priorityDate | 1969-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 34.