http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1338543-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2dbb2d7ecbd600cf89fbdd230f4a466c |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-44756 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J8-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D57-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-44769 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01D57-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C25B9-23 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J8-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-447 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C25B7-00 |
| filingDate | 1972-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1973-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1338543-A |
| titleOfInvention | Method and apparatus for forced flow electrophoresis |
| abstract | 1338543 Electro-phoresis of blood RHONEPOULENC S A 28 March 1972 [30 March 1971] 14459/72 Heading C7B [Also in Division A5] A method for the continuous fractionation of an aqueous liquid containing at least two compounds, the mobilities of which is an electric field vary as a function of the pH, comprises introducing the liquid into an electro-phoresis cell in contact with one face of a filtering membrane, applying an electric field between two electrodes located on either side of the membrane, forcing a fraction of the liquid to pass across the membrane to provide a filtered portion and of removing separately the filtered portion and the unfiltered remaining portion of the liquid; causing a stream of main electrolyte independent of the liquid to be fractionated, to flow in contact with each electrode and causing two streams of auxiliary electrolyte to flow between dialysis membranes which are permiable to ions, said dialysis membranes separating each auxiliary electrolyte stream firstly from the stream of main electrolyte and secondly from the filtered portion of liquid and from the unfiltered removing portion of the liquid respectively, the two streams of auxiliary electrolyte having different average pH between their introduction and removal from the cell. The forced flow electro-phoresis cell 1 is divided into six compartments. The liquid to be treated is passed into compartment 5 where it is subjected to hydrostatic pressure. Part of the liquid filters through membrane 12 and leaves the cell via orifice 21. The unfiltered part leaves through orifice 20. Main electrolyte is introduced simultaneously via orifices 15 and 24 to the anode and cathode compartments 2 and 8 and is removed via orifices 16 and 25. The two portions of main electrolyte are combined in tank 26 and are recirculated. Auxiliary electrolyte is introduced via orifices 17 and 22 into intermediate compartments 4 and 7 and is removed via orifices 18 and 23. The two portions of auxiliary electrolyte are combined in tank 29 and are recycled. The cell temperature is controlled by thermostat 45. The reactant controlling the pH of the auxiliary electrolyte is introduced into tank 29. The electrodes may be stainless steel mesh. The dialysis membranes 11 and 13 may be permeable to ions and molecules M.W. < 500. Membrane 10 is cation selective and membrane 14 is anion selective. The method is particularly suited to the treatment of blood. Gamma globulins may be separated from alpha and beta globulins. The main electrolyte is 0À154N NaOH and the auxiliary electrolyte may be 9 g/l NaCl buffered with 5 g/l sodium citrate. The auxiliary electrolyte may be pH 8À9 in the cathode compartment and pH 7À35-7À45 in the anode compartment. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2225339-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2118975-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2148325-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2553294-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2553295-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5087338-A |
| priorityDate | 1971-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 29.