http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1338294-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_204ea9f0f83d1c51a916e46a41a6a14a |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-28 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C45-59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C49-743 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-46 |
filingDate | 1971-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1973-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | GB-1338294-A |
titleOfInvention | 2-3-2-tetrahydrofuryl-propionyl-1,3-cyclopentanedione and production of this physiologically active compound |
abstract | 1338294 Tetrahydrofuryl - propionyl cyclopentanedione ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI 10 Aug 1971 [21 Aug 1970 1 Sept 1970] 37416/71 Heading C2C The novel compound of Formula (I) may be obtained by hydrogenation of 2[3-(2- furyl) - acryloyl] - 1,3 - cyclopentanedione in the presence of a base and of a hydrogenation catalyst comprising Pt, Pd or Rh, and optionally liberating the free form from its salt by treatment with dilute acid. The starting material may be obtained by aldol condensation of 2-acetyl-1,3-cyclopentanedione with furfural. In an example, 2-(4,5- dihydro - 5 - propyl - 2(3H) - furylidene) - 1,3- cyclopentanedione is obtained as a by-product. Pharmaceutical compositions having hypotensive activity comprise the compound of Formula (I) together with a pharmaceutical carrier in forms suitable for oral or parenteral administration. |
priorityDate | 1970-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.