http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1336441-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d0cb7734bc2e5840db630f0ae7c29684 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-20 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-213 |
filingDate | 1970-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1973-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | GB-1336441-A |
titleOfInvention | Derivatives of cyclo adenosine-3,5-phosphoric acid and their preparation |
abstract | 1336441 Cycloadenosine - 3<SP>1</SP>,5<SP>1</SP> - phosphoric acid derivatives AGENCE NATIONALE DE VALORISATION DE LA RECHERCHE 7 Oct 1970 [10 Oct 1969 2 Oct 1970] 47731/70 Heading C2P The invention comprises (A) an N<SP>6</SP>-, 2<SP>1</SP>-O-, N<SP>8</SP>- and/or N<SP>2</SP>-butyrylated derivative of a compound of Formula I where (a) R 1 and R 2 are hydrogen, one of X and Y is hydrogen or C 1-4 alkyl and the other is C 1-4 alkyl, or (b) X and Y are hydrogen, R 1 is hydrogen, bromine, sulphhydryl, hydroxy, methylthio or amino and R 2 is hydrogen or amino, with the proviso that X, Y, R 1 and R 2 are not all hydrogen; (B) 2<SP>1</SP>-O-butyryl-cycloiso-adenosine-3<SP>1</SP>,5<SP>1</SP>-monophosphoric acid and (C) a salt of (A) or (B) wherein the OH linked to phosphorus is salified. The compounds of the invention may be prepared by reacting a compound of Formula I, or iso-adenosine-3<SP>1</SP>,5<SP>1</SP>- monophosphoric acid or a salt thereof with a butyrylating agent such as butyric anhydride, and optionally forming a salt. The compounds of the invention have a biological activity similar to that of cyclo-AMP. |
priorityDate | 1969-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 27.