http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1335946-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_56ee5285e8e8edccb061046ff20da7a6 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-352 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D309-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-351 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-35 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-495 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D309-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-00 |
filingDate | 1972-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f67d927d30bb6880e6f47faa6c349388 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c4263504355ac1638e5282ae19157979 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e61241551bf480e60a5893aa543399c0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4aa13a7ed81e13432929bbf0807853d9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d02ec230f4110ae5c81a9df8e938507 |
publicationDate | 1973-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | GB-1335946-A |
titleOfInvention | 4- w-coumarin-7-yloxy- alkyl- piperazine derivatives |
abstract | 1335946 Coumarin-7-yloxyalkyl-piperazine derivatives BOEHRINGER MANNHEIM GmbH 11 May 1972 [14 May 1971] 22070/72 Heading C2C Novel compounds of the Formula (I) wherein R 1 is a hydrogen atom or a C 1-5 alkyl radical, R 2 is a C 1-5 alkyl radical, R 3 is an unsubstituted or substituted phenyl or benzyl radical, the substituents, when present, being halogen atoms or C 1-5 alkyl or C 1-5 alkoxy radicals, and n is 1, 2 or 3; and the pharmacologically compatible salts thereof, may be obtained by (a) condensing a compound of the Formula (II) in which X is a halogen atom, with a 7-hydroxy- 3 - R 1 - 4 - R 2 - substituted - coumarin, (b) condensation of a compound of the Formula (IV) with an R 3 -substituted-piperazine, (c) condensation of a compound of Formula (I), in which R 3 is H, with a compound of the formula X.R 3 , in which R 3 is an unsubstituted or substituted benzyl radical; or (d) condensation of a compound of the Formula (VII) with an amine of formula H 2 N-R 3 , and thereafter, if desired, converting the products into their physiologically compatible salts. Pharmaceutical compositions having antiinflammatory and anti-allergic action comprise at least one compound of the Formula (I) in admixture with a solid or liquid pharmaceutical diluent or carrier, for example in the form of tablets or dragees or suspended or dissolved in water or an oil. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4263299-A |
priorityDate | 1971-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 36.