http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1324159-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4b18d70d8bf538fb533d0aa5cf87170d |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-837 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-815 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P35-02 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-11 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-545 |
| filingDate | 1972-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1973-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1324159-A |
| titleOfInvention | Process for producing 7-amino desacetoxy cephalosporanic acid |
| abstract | 1324159 Producing 7-amino-desacetoxycephalosporanic acid TOYO JOZO CO Ltd 14 March 1972 [31 May 1971] 11915/72 Heading C2A [Also in Division C3] 7 - Amino - desacetoxycephalosporanic acid having the formula is produced by N-deacylating a water-soluble salt of 7-phenylacetamido- or 7-phenoxyacetamido-desacetoxycephalosporanic acid with a deacylating enzyme produced by Bacillus megaterium B-400, FERM-P No. 748. The enzyme may be in the form of a culture filtrate of the micro-organism or a purified preparation derived from the filtrate, e.g. the enzyme adsorbed on a non-inactivating carrier (see Division C3). The preferred water-soluble salt of the cephalosporin is the Na or K salt, and the N-deacylation of the salt is effected either by incubating it insolution in a culture filtrate of the micro-organism or by passing its solution through a column of the enzyme adsorbed on an insoluble inert carrier, at pH 7-8 and 30-45‹ C. using a concentration of the salt of 0À1 to 20 mgs./ml. The 7-aminodesacetoxycephalosporin may be recovered by bringing the solution to its iso-electric point (pH 3.7), concentrating, cooling to precipitate the product and washing the precipitate with acetone and drying. |
| priorityDate | 1971-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 21.