http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1319989-A

Outgoing Links

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H13-04
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filingDate 1970-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1973-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber GB-1319989-A
titleOfInvention Lincomycin derivatives and the manufacture thereof
abstract 1319989 Glycosyl isothiouronium halides UPJOHN CO 29 Oct 1970 [3 Nov 1969 (3)] 40742/72 Divided out of 1319988 Heading C2C In a process for converting a trans-glycosyl halide to an isothiouronium halide especially 7-O-methyl-lincosamine isothiouronium bromides by reaction with thiourea, substantial conversion to the cis-isomer is obtained using a tertiary amide dipolar aprotic solvent especially hexamethylphosphoric triamide or DMF. The product may be hydrolysed to the cis-thiose and concomitantly alkylated to form an alkyl cis- 1-thioglycoside optionally in the presence of an antioxidant to prevent oxidation to the bisulphide.
priorityDate 1969-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

Incoming Links

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Total number of triples: 20.