| abstract |
1311956 Potentiated phosphonomycins MERCK & CO Inc 28 Sept 1970 [2 Oct 1969 11 Sept 1970] 46063/70 Heading A5B The antibacterial activity of phosphonomycin antibiotics in non-human animals is potentiated by bringing bacteria into contact with an inducer selected from phosphatides, sugar phosphates and salts thereof, and polyhydric alcohols, whereby an existing phosphonomycin transport pathway in the bacteria is enhanced or a new such pathway is created, and subsequently or simultaneously bringing the bacteria into contact with a phosphonomycin antibiotic. The invention includes compositions comprising a phosphonomycin antibiotic and an inducer as indicated above. |