http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1309223-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J1-0011 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J75-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-013 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C49-713 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C49-617 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C- |
| filingDate | 1971-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1973-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1309223-A |
| titleOfInvention | Process for the manufacture of 4,9-estradien-3-ones |
| abstract | 1309223 #<SP>4,9</SP>-3-Oxosteroids F HOFFMANNLA ROCHE & CO AG 19 Jan 1971 [19 Jan 1970] 2568/71 Headings C2C and C2U d-, l- and dl-Steroids of formula (wherein Z is carbonyl or a group of formula where R<SP>4</SP> is hydroxy, C 1-7 alkoxy or C 1-8 alkanoyloxy and R<SP>5</SP> is H, C 1-7 alkyl, C 2-7 alkenyl or C 2-7 alkynyl, or R<SP>4</SP> and R<SP>5</SP> together form C 1-4 alkylenedioxy; R<SP>1</SP> is C 1-7 alkyl; and R<SP>2</SP> and R<SP>3</SP> are each H or C 1-7 alkyl) are prepared by cyclizing compounds of formula in the presence of a strong organic or inorganic acid or of a salt of an organic or inorganic acid with an organic nitrogen-containing base. The examples relate to the preparation of d- and dl-estra-4,9-diene-3,17-dione. () - 4 - (3,7 - Dioxo - octyl) - 7a - methylperhydroindan-1,5-dione is prepared by chromic oxidation of ()-3-(4-oxopentyl)-6a#-methylperhydrocyclopenta[f][1]benzopyran-4a,7-diol. (+) - 4 - (3,7 - Dioxo - octyl) - 7a# - methylperhydroindan-1,5-dione is prepared by chromic oxidation of ( - ) - 3 α - (4 - hydroxypentyl)- 6a# - methyl - perhydrocyclopenta[f][l]benzopyran. 4a,7#-diol which is itself prepared by hydration of ( -)- 3α - (4 - hydroxypentyl) - 6a# - methyl- 1,2,3,5,6,6a,7,8,9,9a - decahydrocyclopenta[f]- [1]benzopyran-7#-ol. |
| priorityDate | 1970-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 27.