http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1303372-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23K20-116 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D241-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23K50-30 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23K1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23K1-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D241-52 |
| filingDate | 1970-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1973-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1303372-A |
| abstract | 1303372 Quinoxaline - di - N - oxides PFIZER Inc 9 Sept 1970 [3 April 1970] 43229/70 Heading C2C Novel quinoxaline-di-N-oxides of the Formulµ I and II wherein X is hydrogen, methyl, methoxy, trifluoromethyl, bromine, chlorine or fluorine in the 6 or 7 position; R a C 1-3 alkyl group; R 1 is hydrogen or a C 1-3 alkyl group; and Y is bromine or chlorine may be prepared in the case of II by reacting I with an amine R 1 NH 2 or reaction of a benzofuroxan III with an N- substituted 3-hydroxy-3-pyrrolin-5-one and in the case of I by chlorination or bromination of a 3-methyl 2-quinoxaline carboxylic acid ester di-N-oxide which in turn is prepared by contacting a benzofuroxan III with an alkyl acetoacetate in the presence of a base. 1 - Alkyl - 3 - hydroxy - 3 - pyrrolin - 5 - ones may be prepared by reaction of an N-alkylglycine with carbomethoxyacetylchloride in the presence of base to yield an N-alkyl-N-carhomethoxy acetyl glycine ethyl ester which on treatment with strong base yields 1-Alkyl-3-hydroxy 3 - pyrrolin - 4 - carbomethoxy - 5 - one which gives the required compound on decarboxylation. Pharmaceutical compositions of the compounds I and II show bacteriocidal properties and compounds II give growth promotion and improved feed efficiency in animals when administered parenterally or orally with the usual excipients or in the feedstock. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2487352-A1 |
| priorityDate | 1970-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 43.