http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1293843-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-67 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-67 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-056 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-18 |
| filingDate | 1970-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1972-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1293843-A |
| titleOfInvention | A process for the manufacture of pyridine derivatives |
| abstract | 1293843 Pyridoxine F HOFFMANN LA ROCHE & CO AG 19 March 1970 [25 March 1969] 13259/70 Heading C2V Pyridoxine and acid addition salts thereof are obtained by heating a mixture of (a) an oxazolylacetic acid of formula where R<SP>1</SP> is hydrogen or a carboxyl group and R<SP>2</SP> is an alkyl group, with (b) a dioxepine compound of formula where R<SP>3</SP> and R<SP>4</SP> are hydrogen, alkyl or phenyl, and (c) a compound of formula where A and B are in trans-configuration and each represents an electron-withdrawing group, and converting the adduct thereby obtained into pyridoxine or an acid addition salt thereof by rearrangement and acidic hydrolysis. In examples : (a) is 5-ethoxy-4-oxazolylacetic acid. and' 2 - carboxy - 5 - ethoxy - 4 - oxazolylacetic acid, (b) is 2 - isopropyl - 4,7 - dihydro - 1,3- dioxepine and (c) is dimethyl fumarate, diethyl fumarate, di-n-butyl fumarate and fumarodinitrile. Other starting materials are mentioned. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DK-154762-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4339586-A |
| priorityDate | 1969-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 38.