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classificationCPCAdditional http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S530-806
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-35
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-35
filingDate 1970-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1972-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber GB-1293470-A
titleOfInvention Improved allergenic extract and process for preparing same
abstract 1293470 Allergenic extracts MILES LABORATORIES Inc 2 April 1970 [3 April 1969] 15736/70 Addition to 1292434 Heading A5B An extract of an active substance capable of giving an allergenic or antigenic response and containing physiologically active principles is prepared by (1) extracting the active substance with an aqueous extracting fluid; (2) separating the aqueous extracting fluid containing the water-soluble active principles from the insoluble material therein; (3) extracting the insoluble material with an organic solvent for proteinaceous substances; (4) separating the organic solvent containing the organic-solventsoluble active principles from the insoluble material therein; (5) combining the aqueous extracting fluid containing the water-soluble active principles with the organic solvent containing the organic-solvent-soluble active principles and insolubilizing the active principles contained therein by addition of an aluminium compound. The organic solvent may be a heterocyclic tertiary amine such as pyridine, quinoline, lutidine, collidine or picoline; optionally in admixture with an aqueous phase such as aqueous sodium hydroxide. The aluminium compound may be potassium aluminium sulphate or aluminium hydroxide. The insolubilized active principles may be resuspended in a physiologically acceptable aqueous fluid prior to use. The active substance extracted may be pollen, dust, epithelium, mould, insect material, seed, feathers or complex chemicals such as antibiotics.
priorityDate 1969-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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