http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1285302-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5929f2d6f4dba84be8dd3a8ba633db12 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-59 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-12 |
| filingDate | 1970-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1972-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1285302-A |
| titleOfInvention | Pyridine thioacetamide derivatives |
| abstract | 1285302 Thioacetamides TAKEDA YAKUHIN KOGYO KK 7 July 1970 [8 July 1969 27 Sept 1969] 32790/70 Heading C2C Novel compounds I (including salts thereof) where R 1 is H, alkyl, alkoxy or halogen, n is 1 to 4, including the case where (R 1 ) n signifies a divalent straight-chain hydrocarbon radical of 4C which is attached to the 5th and 6th positions of the pyridine ring, R 2 and R 3 are H, alkyl, aralkyl or aryl or together with the adjacent N comprise a heterocycle, and with the proviso that R 1 , R 2 and R 3 are not simultaneously H, are made: (a) by reacting a corresponding -CH 2 CONR 2 R 3 compound with a phosphorus sulphide, or with a halogenating agent and then reacting the product so obtained with hydrogen sulphide; (b) by reacting NHR<SP>1</SP> 2 R<SP>1</SP> 3 with a compound I containing the 2-CH 2 CSNH 2 group, to afford a corresponding I containing a 2-CH 2 CSNR<SP>1</SP> 2 R<SP>1</SP> 3 group (R<SP>1</SP> 2 and R<SP>1</SP> 3 are the same as R 2 and R 3 but are not simultaneously H); and (c) by reacting a corresponding compound with hydrogen sulphide, RCSNH 2 (R is alkyl, aryl or aralkyl) or (R<SP>1</SP>O) 2 P(:S)SH, to afford I containing the 2-CH 2 CS.NH 2 group, or with R 2 NH 2 followed by reaction of the product so obtained with hydrogen sulphide to afford a corresponding I containing a group (R<SP>1</SP> is alkyl). Pharmaceutical preparations useful in treating and/or preventing gastric diseases contain I as active ingredient; suitable forms for administration are, e.g. powders, granules and tablets, and solutions for injection. |
| priorityDate | 1969-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 24.