http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1278406-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6831b19bfc354357342f7c7da79fc162 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C309-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-76 |
filingDate | 1970-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a37c82ee1addc07e60e178cdd42fb7fa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe0ddf9e5ce79a705f9bf8ea04bc2673 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_256400452989c88523cb0c8d11bb57cb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_257cacb7e1351e4ad8f588a9b3c1a420 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_188ec70239db5421d16a45b27f04c7c1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b3f7f7dc32670ede0f0ab0c809715b18 |
publicationDate | 1972-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | GB-1278406-A |
titleOfInvention | Cinnamic acid ester derivatives |
abstract | 1278406 Cinnamic acid esters TANABE SEIYAKU CO Ltd 25 Aug 1970 40734/70 Heading C2C Novel compounds I in which R is phenyl, lauryl, myristyl, cetyl or stearyl; R<SP>1</SP> is H or CH 3 ; R<SP>2</SP> is H or OH; and R<SP>3</SP> is -CH 2 OH when R<SP>2</SP> is OH or R<SP>3</SP> is methacryloyloxy, -CH 2 OH, OH, chloro, chloromethyl or -SO 3 Na when R<SP>2</SP> is H; are prepared by condensing compounds II where X is halo with compounds III in which R<SP>2</SP>' is H and R<SP>3</SP>' is methacryloyloxy, chloro or chloro-methyl; or R<SP>2</SP>' and R<SP>3'</SP> together form -CH 2 O-C(R<SP>4</SP>)(R<SP>6</SP>)-O- in which -C(R<SP>4</SP>)(R<SP>5</SP>)- is the residual moiety of an acetal or ketal; to give compounds IV and if R<SP>2</SP>' and R<SP>3</SP>' form - CH 2 OC(R<SP>4</SP>)(R<SP>5</SP>)-O- eliminating the residual acetal or ketal moiety; or, if desired, where R<SP>3</SP>' is chloro or chloromethyl, hydrolysing the chlorine atom to OH or the chloro-methyl group to hydroxymethyl. Compounds IV where R<SP>2</SP>' and R<SP>3</SP>' form -CH 2 -O-C(R<SP>4</SP>)(R<SP>5</SP>)-O -are isolated as intermediates. Pharmaceutical compositions useful as hypolipemic agents comprise a compound I together with a suitable carrier or diluent. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5187303-A |
priorityDate | 1970-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 29.