http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1272477-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_df92f4f09fe2fe790335ae9b8e7cd9d9 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-165 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C233-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-165 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C237-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-12 |
| filingDate | 1969-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4a2e9356d2869504b5b7034682867b9c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ae9f370da37e2d00225f52cb42b4dc9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d296da72b5520be08baa00abed609d80 |
| publicationDate | 1972-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1272477-A |
| titleOfInvention | 2-hydroxy-5-amino-benzamide derivatives |
| abstract | 1,272,477. 2 - Hydroxy - 5 - aminobenzamide derivatives. SOC. D'ETUDES, DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES ET MEDICALES. 22 June, 1970 [20 June, 1969], No. 31267/69. Heading C2C. The invention comprises novel benzamides of the formula where R is allyl or propargyl; R 1 is H or C 1-5 alkyl; R 2 is C 1-5 alkyl, C 2-5 alkenyl or C 3-6 cycloalkyl, or R 1 and R 2 together with the N atom to which they are attached form a pyrrolidino, piperidino or morpholino radical; R 5 and R 6 are each H or C 1-5 alkyl and, when R 5 and R 6 are both alkyl they are the same; and at least one of R 3 and R 4 is H, the other being H, Cl or CH 3 ; and pharmaceutically acceptable acid addition salts. The compounds of the above formula in which both R 5 and R 6 are H are prepared by hydrolysing the corresponding 5- acetamide derivatives; compounds in which R 5 is H and R 6 is C 1-5 alkyl are obtained by alkylating the corresponding 5-acetamido derivatives and hydrolysing the resulting alkylated products; and compounds in which R 5 and R 6 are the same C 1-5 alkyl are produced by alkylating the corresponding compounds of the above formula in which R 5 and R 6 are H. N - (n - Butyl) - 2 - allyloxy - 5 - (N - methylacetamido) benzamide is obtained by treating N- (n - butyl) - 2 - allyloxy - 5 - acetamidobenzamide with sodium hydride and methyl iodide. Pharmaceutical compositions, suitable for oral administration and having muscle relaxing and anti-inflammatory activities, contain the above novel compounds or therapeutically acceptable acid addition salts thereof and pharmaceutical carriers. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5010108-A |
| priorityDate | 1969-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 36.