http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1265086-A
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D333-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D333-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D333-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D333-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D333-58 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-14 |
filingDate | 1969-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1972-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | GB-1265086-A |
abstract | 1,265,086. o-Aminoalkyl oximes. PHILIPS GLOEILAMPENFABRIEKEN N.V. 15 July, 1969 [18 July, 1968], No. 35554/69. Heading C2C. Novel oxime ethers of Formula I in which A and B together form a benzo group, in which case R<SP>1</SP> is H or CH 3 , R is H or an alkyl group containing from 1 to 5 carbon atoms, and X is O, NH or S, or A and B each represent a hydrogen atom, a methyl group or a halogen atom (Cl, Br or I), in which case X is S, R<SP>1</SP> is H, a halogen atom (Cl, Br or I) or CH 3 , and R is H, an alkyl group containing from 1 to 5 carbon atoms, a cycloalkyl group containing from 3 to 6 carbon atoms, or a phenyl, m- or p-chlorophenyl, 3,4-dichlorophenyl, thienyl-2 or 5- chlorothienyl-2 group, whilst, when A and B each represent a hydrogen atom and X is a sulphur atom, R and R<SP>1</SP> may also together represent a trimethylene group in which case R<SP>1</SP> is bound at the position 2, or an ortho-phenylene or thienylene-2,3 group, in which case R<SP>1</SP> is bound at the position 3, and pharmaceutically acceptable acid addition salts, are prepared by (a) reacting a compound of Formula II in which M is a hydrogen or alkali metal atom, with a compound of formula (or a salt thereof) in which Z is halogen or tosyloxy and Y is H or acyl and, when Y is acyl, hydrolysing the product to remove the acyl group, or (b) reacting a compound of Formula III with a compound of formula or (c) reacting a compound of Formula IV in which Z is halogen or tosyloxy, with ammonia. o - (2 - Bromoethyl) - 2 - hexanoylthiopheneoxime is prepared by reacting 2-hexanoylthiopheneoxime with 1,2-dibromoethane. Pharmaceutical compositions having central nervous system activity, for oral or parenteral administration, comprise a compound of Formula I together with a pharmaceutical carrier. |
priorityDate | 1968-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 43.