http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1263930-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2528034c8a08965ff0728353dcd18b91 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D263-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F8-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D263-34 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F8-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-32 |
| filingDate | 1969-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1972-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1263930-A |
| titleOfInvention | Oxazolyl derivatives |
| abstract | 1,263,930. Oxazole derivatives. ISTITUTO FARMACOLOGICO SERONO S.p.A. 28 Jan., 1969 [31 Jan., 1968], No. 31186/70. Divided out of 1,263,929. Heading C2C. Novel oxazole derivatives of Formula I (in which n is 1 and R<SP>1</SP> is halogen, hydroxy or alkoxy, or n is 2 and R<SP>1</SP> is alkoxy or halogen) are prepared by cyclizing an amide of Formula II (in which n is 1 or 2 and R is alkyl) by treatment. with a cyclizing agent, e.g. phosphorus oxychloride, to give an ester of Formula I in which R<SP>1</SP> is alkoxy, if desired, hydrolysing the ester with alkali to give an acid of Formula I in which R<SP>1</SP> is hydroxy, and, if necessary or desired, reacting the acid of Formula I with a halogenating agent, e.g. thionyl chloride, to give an acid halide of Formula I in which R<SP>1</SP> is halogen. Amides of Formula II are prepared by reacting desylamine or its hydrochloride with a half alkyl ester chloride of malonic or succinic acid. |
| priorityDate | 1968-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 29.