http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1260145-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9b86dbdcfe153c2dfb874aff99d07177 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D333-44 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-44 |
| filingDate | 1968-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_741a11c7157af4f3fa494871e3c21931 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cadeec4c7c717326f696573192d505b0 |
| publicationDate | 1972-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1260145-A |
| titleOfInvention | Nitrothiophene derivatives |
| abstract | 1,260,145. Nitrothiophene derivatives. LILLY INDUSTRIES Ltd. 8 July, 1969 [26 Aug., 1968], No. 40746/68. Heading C2C. Novel compounds of Formula I (in which n is 0 or 1 and Z is phenyl, substituted phenyl, C 1-4 alkyl, C 1-4 haloalkyl or -NR<SP>1</SP>R<SP>2</SP>, where R<SP>1</SP> is H or C 1-4 alkyl and R<SP>2</SP> is C 1-4 hydroxyalkyl or cyclohexyl, or R<SP>1</SP> and R<SP>2</SP>, together with the adjacent nitrogen atom, form aheterocyclic ring optionally substituted by one or more C 1-4 alkyl groups) and acid addition salts thereof, are prepared (a) by reacting a compound of Formula II with a compound of formula X.CH 2 .CO.Z (in which X is halogen) or (b) (when n is 1) by reacting 5-nitrothiophene-2-aldehyde a compound of Formula III and optionally converting a resultant compound to an acid addition salt. Compounds I in which Z is -NR<SP>1</SP>R<SP>2</SP> can also be prepared by reacting compounds I in which Z is haloalkyl with an amine HNR<SP>1</SP>R<SP>2</SP>. Pharmaceutical compositions having antiparasitic activity comprise a compound of the invention together with a pharmaceutical carrier. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5511828-A |
| priorityDate | 1968-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 20.