http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1259387-A
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1611 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2077 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1635 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7004 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-143 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-02 |
filingDate | 1969-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1972-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | GB-1259387-A |
abstract | 1,259,387. Granular material comprising glucofuranosides. CIBA-GEIGY A.G. 31 July, 1969 [5 Aug., 1968], No. 38539/69. Heading A5B. A solid, free-flowing granular material comprising an oily or liquid pharmacologically active glucofuranoside of the formula: wherein R 1 is H, cycloalkyl, benzyl, alkyl, alkenyl or hydroxyalkyl; R 2 is H or alkanoyl; R 3 is allyl, alkyl, benzyl, methylbenzyl or halogenobenzyl and R 5 and R 6 each represent benzyl, methyl benzyl or halogenobenzyl and one of R 3 , R 5 and R 6 may be H, adsorbed on magnesium trisilicate and, if desired, on a further adsorbing agent, and a film-forming agent is prepared by mixing the glucofuranoside with the film-forming agent and an alkanol, working up the mixture so obtained with magnesium trisilicate adsorbent to form a plastic mass which is granulated whilst it is drying. The film-forming agent may be shellac, a polyacrylic or methacrylic ester, an ethylene oxide polymer, a polyvinyl alcohol or an ester thereof e.g. polyvinyl acetate, polyvinylpyrrolidone or copolymers thereof, or a cellulosic derivative which is soluble in alcohol or water e.g. cellulose acetate phthalate, hydroxypropyl-methyl-, ethyl-, ethyl-hydroxyethyl-, hydroxypropyl-, or carboxymethyl cellulose. The further adsorbent may be colloidal silica or cellulose. The glucofuranoside may be ethyl- 3, 5, 6-tri-O-benzyl-O-glucofuranoside or ethyl- 3-O-propyl-5, 6-di-O-para-chlorobenzyl-D-glucofuranoside. Tablets and dragees may be formed from the granular material. |
priorityDate | 1968-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 29.