http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1246006-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d202e9e866984fe229f6facc38f1d740 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D241-26 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D241-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D241-26 |
| filingDate | 1969-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6415a0930f1fbb1d38ed5071f64b7456 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7eeecb28a66fc8abada4f60a3aa753d9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f4b688930899f0af496cc7218306230 |
| publicationDate | 1971-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1246006-A |
| titleOfInvention | Pyrazine derivatives and their conversion to imidazopyrazines |
| abstract | 1,246,006. Diuretic &c compositions. MERCK & CO. Inc. 17 Nov., 1969 [20 Nov., 1968], No. 56181/69. Heading A5B. [Also in Division C2] Pharmaceutical compositions having anti-hypertensive, diuretic and saluretic activity comprise, as active ingredient, a 5-amino-6-chloro- 1H-imidazo [4, 5-6] pyrazin-2-one of the general formula: wherein R<SP>1</SP> is a hydrogen atom or a C 3-7 cycloalkyl, phenyl, C 1-5 alkyl-amidino, C 2-6 alkanoyl-amidino, C 3-5 alkynyl or C 3-5 alkenyl group or a C 1-6 alkyl group optionally substituted by one or more hydroxy, C 1-3 alkoxy, pyridyl, phenyl, halo phenyl and/or -NR<SP>5</SP>R<SP>6</SP> groups, in which R<SP>5</SP> is a hydrogen atom or a C 1-5 alkyl, acetyl or propionyl group and R<SP>6</SP> is a hydrogen atom or a C 1-5 alkyl group or R<SP>5</SP>R<SP>6</SP>N is a saturated 5-6 membered heterocyclic ring optionally containing an imino or C 1-5 alkylimino group or an oxygen atom, and R<SP>2</SP> is a hydrogen atom or a C 1-3 alkyl group or R<SP>1</SP>R<SP>2</SP>N is defined as R<SP>5</SP>R<SP>6</SP>N, or R<SP>1</SP> and R<SP>2</SP> are together a bis (dimethylamino)-methylene group, together with an inert carrier, diluent or coating, and may be administered orally or parenterally as pills, tablets, capsules, elixirs and injeotable preparations. |
| priorityDate | 1968-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 25.