http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1246000-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7f6e33603375c486b0ab3505830af9e8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-082 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-086 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-06043 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-023 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-12 |
| filingDate | 1969-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1971-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1246000-A |
| titleOfInvention | Process for preparing carboxylic acid amides and esters |
| abstract | 1,246,000. Carboxylic acid amides and esters. SANKYO CO. Ltd. 10 June, 1969 [22 Nov., 1968], No. 29461/69. Heading C2C. Carboxylic acid amides and esters are prepared by reacting a carboxylic acid with an amine or an alcohol (i.e. a compound having an OH group attached to a C atom in a hydrocarbyl group or to an N atom) respectively in the presence of (a) a tertiary phosphine, (b) an organic compound of a heavy metal, and (c) (i) an aliphatic or aromatic disulphide, (ii) a compound which under the conditions of the process will react to form an aliphatic or aromatic disulphide, or (iii) an aliphatic or aromatic sulphenyl halide and a base. The reaction is preferably performed in an inert solvent, e.g. methylene chloride, chloroform, acetonitrile or dimethylformamide at room temperature with further functional groups in the carboxylic acid, amine or alcohol protected prior to the reaction. The tertiary phosphine is preferably tributylphosphine or triphenylphosphine; the organometallic compound may be of Hg, Cu, Ag or Pb and the disulphide preferably has the S atom substituted by a halogen atom or an alkyl, phenyl or nitro-substituted phenyl group. Amongst numerous examples the compounds benzoyl-L-leucylglycine ethyl ester and benzyloxycarbonyl tetraglycine ethyl ester are prepared. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2179351-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2179351-A |
| priorityDate | 1968-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 39.