http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1244975-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e45efeaa6a34dfd9d44fa29a7fe0c806 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D513-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D513-10 |
| filingDate | 1968-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1971-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1244975-A |
| titleOfInvention | Benzodioxane derivatives |
| abstract | 1,244,975. Benzodioxane derivatives. YOSHITOMI PHARMACEUTICAL INDUSTRIES Ltd. 11 Dec., 1968 [11 Dec., 1967; 13 Dec., 1967], No. 58916/68. Heading C2C. Novel compounds of formula and acid addition salts thereof wherein R<SP>1</SP> is H, Cl, methyl or methoxy, R<SP>2</SP> is H, C 1-4 alkyl, benzyl or phenyl optionally substituted by Cl, CF 3 , methyl or methoxy, A<SP>1</SP> is -CH 2 -, -CH 2 CH 2 -, -CO-, -CH 2 CO- or -CH(OH)CH 2 -, A<SP>2</SP> is -CH 2 -, -CH 2 CH 2 - or -CH(CH 3 )- and Z is -S-, -SO- or -SO 2 -, are prepared by reacting the compounds of formulµ wherein Y is a reactive radical such as halogen or methyl- or p-tolylsulphonyloxy, or by reaction of a compound of formulµ with HS-A<SP>2</SP>-COOH and R<SP>2</SP>NH 2 optionally with salt formation. 2 - (4 - Oxopiperidinomethyl) 1,4 - benzodioxane is prepared by reaction of 1,4-benzodioxan - 2 - yl methyl methane sulphonate and 4,4-diethoxypiperidine followed by acid hydrolysis. Pharmaceutical compositions in conventional forms for oral or parenteral administration an having vascodilator activity comprise an above novel compound or salt and a carrier or adjuvant. |
| priorityDate | 1967-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 23.