| abstract |
1,241,339. Pyrimidine derivatives. YAMANOUCHI PHARMACEUTICAL CO. Ltd. 17 Oct., 1968 [18 Oct., 1967; 10 June, 1968], No. 49383/68. Heading C2C. [Also in Division A5] Compounds of the general formula (R 1,2 = H, C 1 _ 4 alkyl or hydroxyalkyl, cycloalkyl, aryl or -NR 1 R 2 = heterocyclic ring optionally containing a further hetero-actom, provided that R 1 and R 2 are not both H) are prepared by (a) reacting 2,4-dihydroxy-6- methylpyrimidine with R 1 R 2 NH in the presence of formaldehyde or paraformaldehyde, or (b) reacting a 2,4-dihydroxy-5-halomethyl- 6-methylpyrimidine with R 1 R 2 NH. |