http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1207116-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2e5edd48190cba3fa70dd3975efd9831 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-70 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-22 |
| filingDate | 1969-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2a4d1697b38d804b51d7e3e4f92b5104 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c581720e31308a9ffc4aa3a5392b2f28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba52ab19a35f9fc22e0e0f699b830ea5 |
| publicationDate | 1970-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1207116-A |
| titleOfInvention | Morphanthridine derivatives |
| abstract | 1,207,116. Morphanthridine derivatives. DR. KARL THOMAE G.m.b.H. 6 May, 1969, No. 23114/69. Heading C2C. Novel compounds I wherein R 1 is H or CH 3 , R 2 is H and R 3 and R 4 are methyl; or R 2 together with R 3 or R 4 and the intermediate N and C atoms form a piperidine ring, the other R 3 or R 4 being CH 3 ; and X and Y are H or halo and their acid addition salts are prepared by dehydration of a compound II (wherein R 2 is other than H) or by dehydrogenation of a compound III with an oxidizing agent followed where required by salt formation. 2 - Acetamino - α - (1 - methylpiperidyliden-4- yl)-diphenylmethane is prepared by acetylation of the corresponding 2-amino derivative which in turn is prepared from 2-amino-α-hydroxy-α- (1 -methylpiperid-4-yl)-diphenrylmethane (prepared from 2-amino-benzophenone and 4- chloro-1-methyl-piperidine) by reaction with 80% sulphuric acid. Pharmaceutical compositions comprise a compound I in association with a suitable carrier or diluent, are administered orally, rectally, topically or parenterally and exhibit antihistaminic, sedative, spasmolytic, psychotropic and/or anti-emetic activity and/or an antiserotonine effect. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-3950326-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0019172-A1 |
| priorityDate | 1969-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.