http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1207063-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5929f2d6f4dba84be8dd3a8ba633db12 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-02 |
| filingDate | 1968-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1970-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1207063-A |
| titleOfInvention | A method for producing pentachlorophenyl esters of carboxylic acids |
| abstract | 1,207,063. Pentachlorophenyl esters of aminoacids. TAKEDA YAKUHIN KOGYO K.K. 2 Feb., 1968 [4 Feb., 1967; 26 June, 1967], No. 5487/68. Heading C2C. A process for producing a carboxylic acid ester of the formula wherein R-CO- is an acyl group of a carboxylic acid R.COOH in which each radical attached to the carbon atom in the α-position is weaker than chlorine in electronegativity and which is (1) a hydrocarbon carboxylic acid having at most 20 carbon atoms or (2) an N-protected amine acid or (3) a peptide in which the terminal amino group is protected, comprises reacting an acid R.COOH defined as above with a chlorinated acetic acid ester of the formula wherein Y represents H or Cl, in the presence of a tertiary amine, e.g. triethylamine, or dicyclohexylamine. Examples of the starting materials include alanine, aspartic acid, glycine, isoleucine, leucine, lysine,phenylalanine, tryptophan and valine and glycyl-glycine in which the amino group is protected by a benzyloxycarbonyl or amyloxycarbonyl group, phenylacetic acid and N-t-butoxycarbonyl-L-alanyl-L- phenyl-alanyl-L-isoleucyl glycine. The pentachlorophenyl esters are used in peptide syntheses. |
| priorityDate | 1967-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.