http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1199630-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e109fd00ad68feeeab92ad5d18ff7d78 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-135 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C45-673 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C45-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C45-004 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C45-48 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C45-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C45-67 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B61D7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-135 |
| filingDate | 1967-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1970-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1199630-A |
| titleOfInvention | Phenylethanolamine Derivatives Effective in the Treatment of Bronchospastic Conditions |
| abstract | 1,199,630. Phenylethanolamine derivatives. DRACO, LUNDS FARMACEVTISKA A.B. 18 Oct., 1967 [19 Oct., 1966], No. 47505/67. Heading C2C. Compounds of the general formula (R = tert.-butyl, cyclobutyl, cyclopentyl; R<SP>5</SP> = OH, C 1-5 alkanoyloxy) and their salts are prepared by (a) reducing a compound of the formula (R<SP>3</SP> = H or group replaceable by H) in the presence of RNH 2 , followed by replacement of R<SP>3</SP> if necessary; (b) reacting a compound of the formula with RR<SP>4</SP>NH (R<SP>4</SP>=H, aralkyl), followed by replacement of R<SP>3</SP>'<SP>4</SP>, if necessary; (c) reducing a compound of the formula followed by replacement of R<SP>3</SP>'<SP>4</SP> if necessary; or (d) hydrogenating a compound of the formula reacting the product with cyclobutanone or cyclopentanone, further hydrogenating the reaction mixture and replacing R<SP>3</SP> if necessary; optionally followed in each case by salt formation. The preparation of starting materials for processes (a), (b), (c) and (d) by standard methods and of ethyl 3,5-dihydroxybenzoate, 3,5- dibenzyloxybenzoic acid, 3,5-dibenzyloxybenzoyl chloride, 3,5 - dibenzyloxy - # - bromoacetophenone, 3,5 - dibenzyloxy - # - chloroacetophenone and 3,5-dibenzyloxyacetophenone is described. The compounds of the invention are bronchodilators, and may be administered in the form of pharmaceutical preparations containing them in association with a carrier. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4853381-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111440078-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113264839-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0046144-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110057932-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11427539-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10288602-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11648216-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11357757-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110057932-A |
| priorityDate | 1966-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 45.