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filingDate 1967-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2183e3d6ef77d148a5a357cf42c11f2a
publicationDate 1970-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber GB-1192603-A
titleOfInvention Organophosphines and Organophosphine Compositions having Keratin-Deforming Properties
abstract 1,192,603. Depilatory. AMERICAN CYANAMID CO. 10 April, 1967 (2 May, 1966 (2)], No. 116348/67. Heading A5B. (Also in Division C2 and D1] A composition for the depilation of keratin fibres, e.g. human hair, comprises, in an acceptable vehicle, a tertiary phosphine having one of the formulae:- wherein R and R<SP>1</SP> are the same or different and each is alkyl, alkenyl, cycloalkyl or cycloalkenyl, R<SP>2</SP> and R<SP>4</SP> are each hydrogen or alkyl, R<SP>3</SP> is alkyl or CH 2 Z, R<SP>5</SP> is hydrogen, alkyl or CH 2 Z, Z is OH, unsubstituted amino or COOH and all the Z's in a given compound need not be the same, n is an integer from 1 to 5, m is O '1 or 2 with the proviso that m is 1 or 2 when R<SP>4</SP> and R<SP>5</SP> are both hydrogen and s and q are integers which are never "the same nor are they less than 1 and the sum of s and q is an integer from 3 .to 9, the concentration of the phosphine in the vehicle being at least 0.01 molar and with the proviso that the vehicle does not consist solely of water or an acceptable common organic solvent when the phosphine is one in which (a) is Formula I, Z is OH when n is 1, and R is allkyl when Z is OH 'and n is 2, and (b) in Formula IV Z is OH when n is 1 and (c) when ,the phosphine is tris (2-hydroxypropyl) phosphine. Suitable vehicles for the phosphine are water, poly hydric alcohols, ethanol, isopropanol and the monoethyl ether of ethylene 'glycol, or a cosmetically acceptable cream base. In an example in composition containing bis(hydroxmethy) methyl phosphine, polyoxyethylene (10) cetyl ether, stearyl alcohol-ethylene oxide condansation product, and water, adjusted to pH 12:5, is used for the depilation of laboratory tresses made of human hair. Reference has been directed by the Comptroller to Specification 976,821
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9216304-B2
priorityDate 1966-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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