http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1187259-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_413699f78692c85cc58872be1853cfc3 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-80 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-80 |
filingDate | 1967-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e3cdfdac0a2bb06374ac408ce2337532 |
publicationDate | 1970-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | GB-1187259-A |
titleOfInvention | New Aminoalkyl Esters of 2-Anilino-Nicotinic Acids and process for their manufacture |
abstract | 1,187,259. 2-Anilino-nicotinic acid esters. HEXACHIMIE. 22 Oct., 1968 [23 Oct., 1967], No. 48138/67. Heading C2C. Novel compounds of formula and their acid addition salts with non-toxic acids, especially hydrochlorides, in which A represents a straight or branched lower alkylene radical preferably having 2-4 carbon atoms; R<SP>1</SP> and R<SP>2</SP> taken separately represent lower alkyl radicals, or, taken together with the nitrogen atom to which they are attached, represent a 5- or 6-membered nitrogen-containing heterocyclic structure which may contain another hetero-atom, especially pyrrolidino, piperazino, e.g. 1-phenyl-4-piperazino, piperidino or morpholino; and R<SP>3</SP> and K<SP>4</SP> are identical or different and each represent a hydrogen or halogen atom or a lower alkyl, lower alkoxy or lower halogenalkyl, especially trifluoromethyl, radical (where the term " lower " denotes radicals having at most 4 carbon atoms) are prepared either by reacting an acid of Formula II with an amino alkyl chloride of formula ClANR<SP>1</SP>R<SP>2</SP> or an acid chloride of the acid of Formula II with an amino alcohol of formula HOA.R<SP>1</SP>.R<SP>2</SP>. Pharmaceutical compositions having antipyretic, anti-inflammatory, analgesic and local anaesthetic activity in conventional forms for oral, rectal, topical or parenteral administration comprise an above novel compound or salt and a diluent. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105669531-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008149181-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2007354632-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0016460-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2017105853-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101506168-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11135153-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2509076-C2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2020147604-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9371284-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2623495-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105669531-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008029199-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9872846-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10233198-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11541029-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2015120703-A |
priorityDate | 1967-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.