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filingDate 1969-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1970-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber GB-1184538-A
titleOfInvention alpha-Alkyl-5-Hydroxytryptophan Esters
abstract 1,184,538. Sedatives. UPJOHN CO. 6 Feb., 1969 [16 Feb., 1968], No. 6537/69. Heading A5B. [Also in Division C2] Pharmaceutical compositions in conventional forms for oral and parenteral administration comprise a novel compound of formula having sedative, tranquillizing and antihypotensive activity, wherein R 1 and R 2 are hydrogen or alkyl having from 1 to 6 carbon atoms, inclusive, wherein R 3 is alkyl defined as above, and wherein R 4 is alkyl having from 1 to 12 carbon atoms, inclusive, cycloalkyl having from 3 to 8 carbon atoms, inclusive, phenyl, alkyl substituted phenyl or phenylalkyl having from 7 to 10 carbon atoms, inclusive, and a pharmaceutical diluent and/or another hypotensive agent, a diuretic, a ganglion-blocking agent, a sympathetic blocking agent, a peripheral vasodilator, a tranquillizer, a sedative, a reserpine type compound or a muscle relaxant many examples of which agents are given.
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priorityDate 1968-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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Total number of triples: 27.