http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-118298-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8e60a1b698839af3b2cfa06f716738a2 |
| filingDate | 1917-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1918-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-118298-A |
| titleOfInvention | Improvements in and relating to the Manufacture of Synthetic Drugs. |
| abstract | 118,298. Marks, E. C. R., (Nagai, N.). July 13, 1917. Adrenalin is obtained by the following synthesis :-(1) diacetylprotocatechuic aldehyde, prepared by the reaction of acethy chloride or acetic anhydride on protocatechuic aldehyde, is condensed with nitromethane in the presence of weak inorganic or organic bases ; (2) the resulting diacetyldioxyphenylnitroethanol is reduced in the presence of formaldehyde by means of zinc dust and acetic acid; (3) the diacetyladrenalin so formed is saponified by hydrochloric acid, giving adrenalin hydrochloride. |
| priorityDate | 1917-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 28.